European Academic Research ISSN 2286-4822
ISSN-L 2286-4822
Impact Factor: 3.4546 (UIF)
DRJI Value : 5.9 (B+)
Article Details :
Article Name :
The Effect of Delayed Specimen Separation on Phosphorus and Glucose in Clinical Laboratories in Healthy Adults
Author Name :
Leiza Fuad Hussien, Elham Elamin et al
Publisher :
Bridge Center
Article URL :
Abstract :
Background: Pre-analytical errors are considered the most common causes of inaccurate laboratory results. Delayed separation of blood specimens is a critical factor affecting the stability of various analyses. The objective of this study is to assess the effect of delayed specimen separation on Phosphorus and Glucose in clinical specimens. Methodology: One hundred twenty samples of whole blood were collected from apparently healthy subjects aged 20-40 years, divided into three containers. The first one was centrifuged immediately. The second was delayed for one hour, and the last one was delayed for three hours. Then, glucose and phosphorus were measured. Results: Significant increase between one and 3 hours in the phosphorus level, and decrease between one and 3hours in the glucose level when compared to baseline time. Conclusion: Phosphorus is elevated, while glucose undergoes glycolysis in erythrocytes and leukocytes, causing progressive declines in measurable levels. The review highlights mechanisms, timelines of degradation, and strategies to ease these effects, including prompt centrifugation, use of glycolysis inhibitors, and adherence to standardized protocols.
Keywords :
Effect of Delayed Specimen Separation, Phosphorus, Glucose, Clinical Laboratories
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